Lignans and related compounds
Apexbio Technology LLC Etoposide 33419-42-0 10mM (in 1mL DMSO)
Etoposide (VP-16) is a topoisomerase II inhibitor widely used in biomedical research to study mechanisms of DNA damage and cancer therapy It forms a stabilized complex with DNA and topoisomerase II preventing the enzyme-mediated religation of cleaved DNA strands Resulting DNA double-strand breaks lead to apoptosis particularly in rapidly dividing cancer cells Reported IC50 values vary across cell lines such as 59 2 M for topoisomerase II inhibition 30 16 M in HepG2 and 0 051 M for MOLT-3 indicating differential cytotoxic responses to etoposide in various cancer cell models
Apexbio Technology LLC Podophyllotoxin 518-28-5 20mg
Podophyllotoxin (CAS 518-28-5) is a naturally occurring lignan that acts as a microtubule assembly inhibitor by binding to tubulin thereby disrupting mitotic spindle formation and inhibiting cell division This mechanism underlies its antineoplastic activity making it a valuable tool in studies of cell cycle regulation cytoskeletal dynamics and anticancer drug development Podophyllotoxin is widely used in biomedical research to investigate mechanisms of cytotoxicity and to screen for compounds targeting mitotic pathways The compound is supplied as 100 mg in a glass bottle or 50 mg in a poly bottle
Sigma Aldrich Fine Chemicals Biosciences Rubrene sublimed grade, 99.99% trace metals basis | 517-51-1 | MFCD00003703 | 5G
Rubrene sublimed grade, 99.99% trace metals basis | Purity: 99.99% trace metals basis | Mol Wt: 532.67 | 517-51-1 | MFCD00003703 | 5G
AdipoGen Podophyllotoxin
Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.
Medchemexpress LLC N-demethyl ivabradine-d6 hydrochloride | 98.0% | 497.06 g/mol | C26H29D6ClN2O5 | 5 MG
N-Demethyl Ivabradine-d6 hydrochloride is the deuterium-labeled N-demethyl metabolite of ivabradine supplied as the hydrochloride salt. It is provided as a solid powder intended for use as an analytical standard or tracer in quantitative NMR, GC-MS, or LC-MS applications.
- Deuterium-labeled (d6) analogue for use as an internal standard.
- High purity (98.0%).
- Provided as a hydrochloride salt in solid powder form.
- Available in small analytical pack sizes suitable for assay development.
- Storage stability: powder -20°C (3 years) or 4°C (2 years).
- Suitable as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS.
Pfanstiehl Inc Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5
Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5
Medchemexpress LLC 9-Cyclopentyladenine Monometha | HY-116530-10MM-1ML-RECONS
9-Cyclopentyladenine Monometha
Medchemexpress LLC Anthracene-9-carboxylic acid-d9 | 1219803-78-7 | 98.9% | 231.29 | C15HD9O2 | 10 MG
Anthracene-9-carboxylic acid-d9 is the deuterium-labeled analogue of anthracene-9-carboxylic acid used as a laboratory reagent and tracer in biochemical and electrophysiological studies. It is commonly used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types.
- Deuterium-labeled analogue for tracer and isotopic studies.
- Reported purity 98.9%.
- Molecular formula C15HD9O2; molecular weight 231.29.
- CAS number 1219803-78-7 for unambiguous identification.
- Available in small pack sizes suitable for research (e.g., 10 mg).
- Supplied with certificate of analysis and safety data sheet.
Chemscene ChemScene | 9-Bromo-10-phenylanthracene | 25G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23
ChemScene | 9-Bromo-10-phenylanthracene | 25G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23
Medchemexpress LLC O-demethyl lenvatinib hydrochloride | 00-00-0 | 97.1% | C20H18Cl2N4O4 | 10MG
O-demethyl lenvatinib hydrochloride is the hydrochloride salt of the O-demethyl metabolite of lenvatinib, supplied for research use as a solid or as a 10 mM solution in DMSO. It is intended as a reference standard and tool compound for biochemical, cellular, and metabolism studies. Typical listed purity is 97.1% and molecular weight (salt) is 449.29 g·mol-1.
- Hydrochloride salt form for improved solubility in polar solvents.
- Available as solid and as a 10 mM solution in DMSO.
- High purity suitable for analytical and reference standard use.
- Applicable to metabolism, pharmacokinetic, and biochemical studies.
- Supplied in small pack sizes suitable for research-scale experiments.
Chemscene ChemScene | 9-Bromo-10-phenylanthracene | 10G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23
ChemScene | 9-Bromo-10-phenylanthracene | 10G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23
Pfanstiehl Inc Podophyllotoxin (P-126) 500g pack API, active pharmaceutical ingredient CAS: 518-28-5
Podophyllotoxin (P-126) 500g pack API, active pharmaceutical ingredient CAS: 518-28-5